Satellite cell proliferation and skeletal muscle hypertrophy
نویسندگان
چکیده
منابع مشابه
Satellite Cell Proliferation in Adult Skeletal Muscle
England et al. (1990), Very mild muscular dystrophy associated with the deletion of 46% of dystrophin., Nature, 343:180-182. Gilboa et al. (1986), Transfer and Expression of Cloned Genes Using Retroviral Vectors., Biotechniques, 4(6):5O4-5 12. Allbrook, D. (1981), Skeletal Muscle Regeneration, Muscle and Nerve, 4:234-245. Ishiura et al. (1986), Biochemical Aspects of Bupivacaine-Induced Acute M...
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The largest mammalian cells are the muscle fibers, and they have multiple nuclei to support their large cytoplasmic volumes. During hypertrophic growth, new myonuclei are recruited from satellite stem cells into the fiber syncytia, but it was recently suggested that such recruitment is not obligatory: overload hypertrophy after synergist ablation of the plantaris muscle appeared normal in trans...
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An important unresolved question in skeletal muscle plasticity is whether satellite cells are necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7-DTA) was created which enabled the conditional ablation of >90% of satellite cells in mature skeletal muscle following tamoxifen administration. To test the hypothesis that satellite cells are necessary for skelet...
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Ursolic acid (UA) is known as a naturally occurring triterpene pentacyclic compound in some medicinal herbs including savory that affects the skeletal muscle. In the current study, the effect of UA was evaluated on C2C12 cells and satellite cells (SCs) isolated from native broiler chicks. First in the in vitro experiment, the C2C12 cell line obtained from the Stem Cell Technology Research Cente...
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Follistatin (FS) inhibits several members of the TGF-beta superfamily, including myostatin (Mstn), a negative regulator of muscle growth. Mstn inhibition by FS represents a potential therapeutic approach of muscle atrophy. The aim of our study was to investigate the mechanisms of the FS-induced muscle hypertrophy. To test the role of satellite cells in the FS effect, we used irradiation to dest...
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ژورنال
عنوان ژورنال: Applied Physiology, Nutrition, and Metabolism
سال: 2006
ISSN: 1715-5312,1715-5320
DOI: 10.1139/h06-053